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Post by mhbruin on Sept 16, 2023 8:25:35 GMT -8
What's the difference between a poorly dressed man on a bicycle and a nicely dressed man on a tricycle? A tire.
Who Knew? There Are Actual Republicans Who Want to Govern...At Least a Few
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Post by mhbruin on Sept 16, 2023 8:26:19 GMT -8
Epic Fail
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Post by mhbruin on Sept 16, 2023 8:28:38 GMT -8
Reverse Vaccines Don't Make It More Likely You Get COVID
Autoimmune disorders — where the immune system mistakes something harmless in the body for a pathogen or threat — are not much fun for the people who are stuck with them. And these disorders have been gradually increasing in prevalence over the last couple of decades. I’ve got one myself. Lucky me! Actually, I am lucky in a way, because with treatment, mine is currently under control. But treating autoimmune disorders generally means dampening the immune system as a whole, and that increases risk for infections, cancers, and other things that a healthy immune system can help stop.
So the more specific we can get with these treatments, the better. The best thing of all would be to somehow let the immune system know that whatever it keeps mistakenly attacking (usually a protein) is actually OK, and so it should leave that particular thing alone but otherwise keep on keepin’ on. But how could we do that? We do know very well how to prime the immune system to go after something specific, for example by giving a vaccine. But how do we get it to leave a specific thing alone, especially if it’s already started attacking that thing?
Well, thanks to efforts centered at the University of Chicago, we’ve got the basics down for how to do this. The body has ways to designate proteins as “safe” — if it didn’t, our immune system would just go crazy and attack everything — and we’ve recently learned a lot more about how that works. In a September 7 article in Nature Biomedical Engineering, D. Scott Wilson, Jeffrey A. Hubbell, and their colleagues describe how they took advantage of this emerging knowledge to design “inverse vaccines”.
Their first successes? Reducing pathology to zero in mice with encephalomyelitis (the mouse analog of multiple sclerosis) and reversing the established immune response to a simian immunodeficiency virus (SIV) vaccine in macaques. What’s really important here is that an already-established immune response to something very specific can be knocked down, because that is what we will need to do to treat autoimmune disorders in humans without compromising the immune system:
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Post by mhbruin on Sept 16, 2023 8:30:04 GMT -8
A Benefit Isn't a Benefit If You Don't Get the Benefit of It.
If you’ve ever tried to get one of the many benefits offered by the federal government to help people out in need, you’ve probably run into a thorny problem: time-consuming and often confusing paperwork.
The federal government offers a plethora of benefits designed to help alleviate poverty and help those in dire straits, whether it’s Medicaid, disability, food assistance, unemployment insurance ― or any of the thousands of other programs offered from farm loans to disaster relief. But too often, the discovery and application processes are designed not to facilitate enrollment, but rather to hinder those trying to sign up.
Fewer than 50% of those eligible for Medicaid are signed up for it. More than half of those potentially eligible for unemployment insurance in 2022 did not apply because they weren’t aware they were eligible. And 28% of those eligible for supplemental food assistance ― colloquially known as food stamps ― do not receive it. Recent scholarship from academics and government agencies shows that paperwork burdens and informational hurdles impose a real cost on people seeking to access benefits, reducing enrollment, kicking people off of programs they’re eligible for, and making it hard to learn about them in the first place. And these costs perpetuate inequality and poverty.
The Biden administration is finally trying to do something about this.
In an executive order issued in 2021, President Joe Biden directed agencies to reduce burdens and improve customer experience for government benefit programs with the aim of helping everyone who is eligible to be able to access and receive benefits.
“Biden is really the first to try to tackle this as a whole in the agencies across the executive branch,” said Pamela Herd, an expert on administrative burdens at Georgetown University.
This is part of Biden’s hope to restore faith in government by showing that it can work for Americans. Making government work requires doing the big things, like the new industrial policy vision embedded in the Inflation Reduction Act and CHIPS Act, and also the small things, like eliminating barriers people face to get health care or housing or unemployment insurance.
While agencies have been taking on this work for some time, this is the first presidential directive running through the Office of Management and Budget (OMB) that seeks to make burden reduction a permanent part of the culture of the federal bureaucracy.
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Post by mhbruin on Sept 16, 2023 8:32:06 GMT -8
This Won't do a Thing Unless the Judge is Ready to Enforce It.
The US special counsel prosecuting Donald Trump for election subversion has asked a judge to impose “limited restrictions” on the former president’s public statements, citing his frequent “inflammatory attacks” on the court, prospective witnesses and citizens of Washington DC.
In a filing on Friday, federal prosecutors requested that judge Tanya Chutkan issue a “narrow” gag order that would prohibit Trump from making statements “regarding the identity, testimony, or credibility of prospective witnesses” and “about any party, witness, attorney, court personnel, or potential jurors that are disparaging and inflammatory, or intimidating”.
Related: Trump lawyer Jenna Ellis turns on ‘malignant narcissist’ ex-president
The request noted his “near-daily” disparaging posts on social media site Truth Social, including his post after his arraignment that said, “IF YOU GO AFTER ME, I’M COMING AFTER YOU”; claims that the justice system is “rigged” against him; attacks on DC as a “filthy and crime ridden” district where he says he will not get a fair trial and direct attacks on Chutkan, including calling her “a fraud dressed up as a judge” and “radical Obama hack”.
Throw His Ass in Jail if You Can Find a Cell Big Enough for His Ass and His Ego
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Post by mhbruin on Sept 16, 2023 8:34:56 GMT -8
Father Doesn't Necessarily Know Best ... And You May Not Be Able to Find Father
Gone are the white picket fences, the two-and-a-half children in the suburbs, and married parents. The American nuclear family is officially dead, according to a new analysis from the Pew Research Center — even if some Americans haven't accepted it.
In 1970, nearly 70% of American adults ages 25 to 49 were living with a spouse and at least one child. As of 2021 — the most recent year for which they have data — that's fallen to 37%. At the same time, other family arrangements have become more common: In 1970, essentially no one was reported to be cohabitating unmarried with kids; by 2021, that rose to 5%. And, significantly, 18% of American adults were married with no kids in 1970. As of 2021, that's risen to 21%.
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Post by mhbruin on Sept 16, 2023 8:37:10 GMT -8
Could She Be the First Domino to Flip? (In Today's Mixed Metaphor)
Jenna Ellis – the Donald Trump lawyer who like the former president faces criminal charges regarding attempted election subversion in his defeat by Joe Biden in 2020 – says she will not vote for him in the future because he is a “malignant narcissist” who cannot admit mistakes.
“I simply can’t support him for elected office again,” Ellis said. “Why I have chosen to distance is because of that frankly malignant narcissistic tendency to simply say that he’s never done anything wrong.”
Ellis, 38, was speaking on her show on American Family Radio, a rightwing evangelical network run by the American Family Association, a non-profit that by its own description has been “on the frontlines of America’s culture war” since 1977.
Ellis was one of 18 Trump associates charged with him in Georgia over attempts to overturn Biden’s victory there. Charged with violating state anti-racketeering laws and solicitation of violation of an oath by a public officer, she was granted $100,000 bail and pleaded not guilty.
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Post by mhbruin on Sept 16, 2023 8:40:07 GMT -8
Shut it off, shut it off. Buddy, now I shut you down
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Post by mhbruin on Sept 16, 2023 8:46:00 GMT -8
Lauren Boebert Reaches Across the Aisle
Rep. Lauren Boebert's night inside a Denver theater was way more handsy than it initially appeared -- new video shows her groping her date's crotch as he aggressively paws at her breast.
In the new surveillance video clip -- recorded Sunday night during a performance of "Beetlejuice" -- Boebert's date first reaches over to fondle her right breast, and almost immediately she puts a hand in between his legs.
The groping of her chest continues throughout the clip, and eventually the U.S. Congresswoman puts her other hand in his crotch as well.
As we previously reported, other clips revealed Boebert was also illegally vaping inside the theater -- something she had denied -- and that eventually got her and her date kicked out of the performance. For good measure, she flipped off a theater employee on the way out.
Just Don't Say Her Name Three Times.
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hasben
Resident Member
Posts: 1,047
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Post by hasben on Sept 16, 2023 11:42:35 GMT -8
Most Concerning GOP Cuts
What that demonstrates to me is that 40 something percent of gop voters are sadistic, racist, fascists who hate children other than their own. That's your maga base.
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hasben
Resident Member
Posts: 1,047
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Post by hasben on Sept 16, 2023 11:46:27 GMT -8
Lauren Boebert Reaches Across the Aisle
She needs to stay home in her trailer to play boobs and tubes in front of her kids.
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Post by mhbruin on Sept 17, 2023 8:17:03 GMT -8
Lauren Boebert Reaches Across the Aisle She needs to stay home in her trailer to play boobs and tubes in front of her kids. It is interesting that most of the media have focused on her vaping and taking flash picutres, and not her indecent behavior.
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