Post by mhbruin on Mar 12, 2023 12:26:59 GMT -8
Is It Easier to Convert a Cancer Cell Than a QANON Person?
Dr. Ravindra Majeti and his team at Stanford University School of Medicine have found a way to take a patient’s own cancer cells and directly convert them into immune cells — to “switch teams”, in effect, with all their idiosyncracies remaining in place. This way the immune system gains a whole lot of information about exactly which targets to recognize and attack in that particular patient’s cancer, so that a therapeutic design does not need to rely on best guesses.
They demonstrated a potent stimulation of essentially customized T cells both in live mice and in cultured human cells. In mice, this led to a complete eradication of leukemia and even a strong response against solid tumors.
“When we first saw the data showing clearance of the leukemia in the mice with working immune systems, we were blown away,” said Majeti. “We couldn’t believe it worked as well as it did. What’s more, we showed that the immune system remembered what these cells taught them. When we reintroduced cancer to these mice over 100 days after the initial tumor inoculation, they still had a strong immunological response that protected them.”
Today I was late writing stuff because I was attending the funeral of a friend who went through 14 years of fighting cancer. I wish some of the miracles in the pipeline had been here to help him.